|
|
|
|
|
|
|
|
|
|
Subset name |
Abbreviation |
Definition |
|
Disease name |
Abbreviation |
|
|
|
CD4 T cells |
|
|
|
ANCA-associated vasculitis |
AAV |
|
|
|
Naïve CD4 T
cells
|
Naïve CD4 |
CD3+/CD4+CD8-/CCR7+CD45RA+ |
|
Takayasu arteritis |
TAK |
|
|
|
Memory CD4 T
cells
|
Mem CD4 |
CD3+/CD4+CD8-/non-naive CD4+/CD25- |
|
Adult-onset Still's disease |
AOSD |
|
|
|
T helper 1 cells
|
Th1 |
CD3+/CD4+CD8-/non-naive CD4+/CD25-/CXCR5-CCR6-/CXCR3+CCR4- |
|
Behçet's disease |
BD |
|
|
|
T helper 2 cells
|
Th2 |
CD3+/CD4+CD8-/non-naive CD4+/CD25-/CXCR5-CCR6-/CXCR3-CCR4+ |
|
Rheumatoid arthritis |
RA |
|
|
|
T helper 17 cells
|
Th17 |
CD3+/CD4+CD8-/non-naive CD4+/CD25-/CXCR5-CCR6+/CXCR3- |
|
Systemic sclerosis |
SSc |
|
|
|
T follicular
helper cells
|
Tfh |
CD3+/CD4+CD8-/non-naive CD4+/CD25-/CXCR5+ |
|
Ideopathic inflammatory myopathy |
Myo |
|
|
|
Fraction II effector regulatory T cells
|
Fr. II eTreg |
CD3+/CD4+CD8-/CD25++CD45RA- |
|
Sjögren's syndrome |
SjS |
|
|
|
Fraction I naïve regulatory T cells
|
Fr. I nTreg |
CD3+/CD4+CD8-/CD25+CD45RA+ |
|
Mixed connective tissue disease |
MCTD |
|
|
|
Fraction III non-regulatory T cells
|
Fr. III T |
CD3+/CD4+CD8-/CD25+CD45RA- |
|
Systemic lupus erythematosus |
SLE |
|
|
|
CD8 T cells |
|
|
|
*Healty controls |
HC |
|
|
|
Naïve CD8 T
cells
|
Naïve CD8 |
CD3+CD19-/CD4-CD8+/CD45RA+CCR7+ |
|
|
|
|
|
|
CD8+ T effector memory CD45RA+ cells
|
TEMRA CD8 |
CD3+CD19-/CD4-CD8+/CD45RA+CCR7- |
|
|
|
|
|
|
Effector Memory CD8 T cells
|
EM CD8 |
CD3+CD19-/CD4-CD8+/CD45RA-CCR7- |
|
|
|
|
|
|
Central Memory CD8 T cells
|
CM CD8 |
CD3+CD19-/CD4-CD8+/CD45RA-CCR7+ |
|
|
|
|
|
|
B cells |
|
|
|
|
|
|
|
|
Naïve B cells
|
Naïve B |
CD3-CD19+/IgD+CD27- |
|
|
|
|
|
|
Unswitched
memory B cells
|
USM B |
CD3-CD19+/IgD+CD27+ |
|
|
|
|
|
|
Switched
memory B cells
|
SM B |
CD3-CD19+/IgD-CD27+/CD38- |
|
|
|
|
|
|
Double
Negative B cells
|
DN B |
CD3-CD19+/IgD-CD27- |
|
|
|
|
|
|
Plasmablasts
|
Plasmablast |
CD3-CD19+/IgD-CD27++/CD38+ |
|
|
|
|
|
|
Natural Killer cells |
NK |
CD3-CD19-/CD14-/CD56+ |
|
|
|
|
|
|
Monocytes |
|
|
|
|
|
|
|
|
CD16 positive
monocytes
|
CD16p Mono |
CD3-CD19-/HLARDR+/CD56-/CD14+CD16+ |
|
|
|
|
|
|
Non-classical monocytes
|
NC Mono |
CD3-CD19-/HLARDR+/CD56-/CD14dimCD16+ |
|
|
|
|
|
|
Intermediate monocytes
|
Int Mono |
CD3-CD19-/HLARDR+/CD56-/CD14++CD16+ |
|
|
|
|
|
|
Classical
monocytes
|
CL Mono |
CD3-CD19-/HLARDR+/CD56-/CD14+CD16- |
|
|
|
|
|
|
Dendric cells |
|
|
|
|
|
|
|
|
Myeloid
dendritic cells
|
mDC |
CD3-CD19-/HLARDR+/CD56-/CD14-CD16-/CD11c+CD123- |
|
|
|
|
|
|
Plasmacytoid
dendritic cells
|
pDC |
CD3-CD19-/HLARDR+/CD56-/CD14-CD16-/CD11c-CD123+ |
|
|
|
|
|
|
Neutrophils |
Neu |
Immune-magnetically
sorting with the "MACSxpress Neutrophil isolation Kit, human" |
|
|
|
|
|
|
Low-Density Granulocytes
|
LDG |
SSChigh
/CD16+CD15+/CD14-
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|